Reporting to head of biology, lead a group of in vitro assay biologists, coaching group members to improve skills and productivity

Independently design, conduct, optimize and proactively troubleshoot screening assays

Develop, optimize and validate biophysical, biochemical and cell-based assay platforms for the hit identification, lead optimization and functional characterization of small molecules

Work on the bench implementing state-of-the-art technologies for the different assay platforms- managing motivating and training junior members within the group

Ensure robust and high-quality assays with efficient use of automation and instrumentation

Data processing, interpretation and presentation to cross-functional team members

Proposing, planning, quoting, tracking reagent needs, usage and executing timelines for each study

Work closely with other biology groups involved in cellular and molecular biology, protein biology/chemistry, and ADME, offering integrated drug discovery support alongside chemistry for multiple client-based projects

Strong experience  of working with small-molecule drug discovery from a CRO/Drug Discovery company/Translational Research with an ability to efficiently handle time-bound and service-based projects

Should have a minimum of 2 years experience in the relevant profile.

Broad research experience in cell-free and cell-based assay development like using luminescence and fluorescence-based methods. E.g. FRET, TR-FRET, FP, Anisotropy, HTRF, BRET, AlphaScreen, etc. (however not limited)

Experience working with board target classes -e.g. enzymes, GPCRs, transporters, ion channels, surface receptors, etc. across different therapeutic areas

Strong experience in medium and high-throughput screening using cell-free and cell-based assays

Experience with binding assays - particularly hands-on experience with Surface Plasmon Resonance (SPR) or Microscale Thermophoresis (MST) will be an advantage

Ability to plan and design experiments, order reagents, set up assay platforms and deliver them in a timely fashion

Experience in the generation of stable cell lines required for cell-based assay development and screening

Understanding of basic molecular biology, cell biology and biochemistry experiments will be an advantage

Managerial experience of junior scientists

Excellent data analysis and interpretation skills

Ability to participate in project team meetings and contribute to the project(s) intellectually

Ability to overcome technical challenges and exercise sound judgment under pressure

High self-motivation to initiate projects and work independently under aggressive deadlines

Should have strong technical knowledge with exceptional attention to detail

An excellent personal rapport and an ability to engender trust and respect

An ability to work well as part of a small focussed team and build relationships

An exceptional communication skills and ease in interaction with all stakeholders

An infectious enthusiasm for life, work and making a difference to the world in which we live

A bright, friendly, flexible personality with agility to switch between different skill sets

An exceptional organisational skills that thrive working in a fast-paced and vibrant team environment

Positivity, focus, and a winning mentality allied with kindness

Curiosity, energy, creativity, and bravery with a strong desire to help to build the o2h culture.